The manufacturing processes that result in medical devices are regulated and governed by laws and standards (1). For any new medical device – including those made via 3D printing – these regulations must be adhered to. A key aspect of my research is to invent, identify and develop new manufacturing processes at the university level that are compliant with these laws to assist in the clinical translation of a specific implant (2). This includes using aqueous-based systems where possible (3), developing melt-based processing  (4) and initiator/catalyst-free polymerization schemes (5). The MEW process is an example of this philosophy, and is applicable to the manufacture of medical devices for the clinic.


  1. Youssef A, Hollister S, Dalton PD. (2017) Additive manufacturing of polymer melts for implantable devices and scaffolds. Biofabrication, 9, 012002.
  2. Hicks CR, Chirila TV, Clayton AB, Fitton H, Vijayasekaran S, Dalton PD, Lou X, Platten S, Ziegelaar BW, Hong Y, Crawford GJ, Constable IJ (1998) Clinical results of implantation of the Chirila keratoprosthesis in rabbits. Br J Ophthalmol, 82, 18-25.
  3. Dalton PD, Flynn L, Shoichet MS (2002) Manufacture of poly(2-hydroxyethyl-co-methyl methacrylate) hydrogel tubes for use as nerve guidance channels. Biomaterials, 22, 3843-3851.
  4. Brown TD, Dalton PD, Hutmacher DW. (2011) Direct Writing by Way of Melt Electrospinning. Adv Mater, 23, 5651-57.
  5. Komma M (2015) Oberflächenmodifikation von Poly(ε-caprolacton) Scaffolds mittels Self-Initiated Photografting and Photopolymerization. University of Würzburg, Bachelor Thesis.